You can approximate a sine wave with a high frequency PWM that is filtered/averaged by further circuitry.
There is no limit on the minimum PWM frequency - you can always make your program slower. You can only update the PWM value a few thousand times per second, so the maximum is probably less than 1000 Hz.
I think you should use a very short PWM period. You can have almost 10-bit resolution with a 47 kHz PWM (period = 1020) or 8-bit resolution with ~200 kHz PWM (period = 255).
I have no idea what you mean by “number of clocks data” or “command reference set”, but the entire Maestro documentation is here. In particular, please look at the “Set PWM” serial command and tell me if you need more information than what it says there.
We do not have that data. It will be different for every command and sometimes even depends on the arguments to the command. Also, there are other tasks being performed by the Maestro in between executing script commands, so the speed of your program will depend on what else you are doing.